The Optimizing Process of the Blood Coagulation Powder Composition With Response Surface Methodology

Zarei, Reza; Mirmasoudi, Seyyedeh Sahra; Feizkhah, Alireza; Pourmohammadi Bejarpasi, Zahra; Shahrousvand, Mohsen

doi:10.22124/cse.2023.23925.1051

Document Type : Original Article

Authors

¹ Department of Statistics, Faculty of Mathematical Sciences, University of Guilan, Rasht, Iran.

² Burn and Regenerative Medicine Research center, Guilan University of Medical Sciences, Rasht

³ Department of Medical Physics, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran

⁴ Burn and Regenerative Medicine Research center, Guilan University of Medical Sciences, Rasht, Iran

⁵ Caspian Faculty of Engineering, College of Engineering, University of Tehran, Tehran, Iran

https://doi.org/10.22124/cse.2023.23925.1051

Abstract

This study focuses on optimizing process of the blood coagulation powder composition with response surface methodology. For this purpose, optimizing the synthesis conditions of powder composition, the response surface methodology (RSM) was used by Box-Behnken design (BBD). The variables of this method were sodium alginate (A) and zinc oxide nanoparticles (B), prepared in combination with a fixed percentage of shell powder and measured for different reactions. results showed that according to the response surface methodology, which is the most optimal case, to introduce this method as a suitable suggestion for this kind of problem in the applications of vascular surgeries, burns, etc., and direct to future pre-clinic and clinical studies.

Keywords

References

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Computational Sciences and Engineering

The Optimizing Process of the Blood Coagulation Powder Composition With Response Surface Methodology

References

References

Volume 2, Issue 2
September 2022
Pages 311-322

The Optimizing Process of the Blood Coagulation Powder Composition With Response Surface Methodology

References

References

Volume 2, Issue 2September 2022Pages 311-322

Volume 2, Issue 2
September 2022
Pages 311-322